FDA Has Broad Regulatory Options for Mixing Covid Boosters

U.S. vaccine regulators have broad authority to allow mix-and-match Covid-19 vaccine boosters under their emergency powers, even if Johnson & Johnson and other companies don’t apply for it.

The Food and Drug Administration appears poised to clear heterologous boosting, which would allow someone who’s eligible for a booster to get an additional shot that’s different from their original vaccine. Preliminary results from a National Institutes of Health study indicate mixing Covid-19 vaccines as a booster can produce the same or even more antibodies compared with using the same vaccine for all shots. The study found the strongest antibody response ...