Vaccine Mix-and-Match Approach Poised to Get FDA Clearance

The U.S. Food and Drug Administration is poised to clear the use of a Covid-19 booster from a different manufacturer than the one that supplied a patient’s original inoculation, according to people familiar with the matter.

The FDA is still considering the scope of the measure, including whether to allow the widespread mixing and matching of vaccines or whether to narrow the parameters of use, the people said, speaking on condition of anonymity before any announcement.

The FDA declined to comment and it’s not clear when a decision will be announced. Allowing mixing-and-matching would be the agency’s first such clearance ...