Lilly’s Zepbound Plus Arthritis Drug Taltz Eases Joint Pain

Patients given a combination of Eli Lilly & Co.’s weight-loss shot Zepbound and arthritis drug Taltz saw a greater improvement in tender and swollen joints compared to those on Taltz alone, a new study found.

The Lilly-backed research enrolled 271 patients with obesity and active psoriatic arthritis — an autoimmune disease that can cause stiffness, swelling and patchy, red skin. It then tested whether adding Zepbound increased the effectiveness of the company’s blockbuster arthritis drug.

The combination unsurprisingly was more effective at helping patients lose weight and control the arthritis than Taltz alone, the main goal of the trial. ...