FDA Warns of Rare but Serious Skin Reactions With Pain Reliever Acetaminophen

The Food and Drug Administration Aug. 1 said it is informing the public that acetaminophen has been associated with a risk of rare but serious skin reactions.

These reactions, known as Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and acute generalized exanthematous pustulosis (AGEP), can be fatal, FDA said. Acetaminophen is a common active ingredient to treat pain and reduce fever; it is included in many prescription and over-the-counter (OTC) products.

Reddening of the skin, rash, blisters, and detachment of the upper surface of the skin can occur when using drug products that contain acetaminophen, the agency said. These reactions ...