Clinical DNA Lab Tests Fail to Analyze 25% of Genes, Study Finds (1)

Doctors who rely on next-generation DNA tests could be missing valuable chunks of information that prevent them from accurately diagnosing genetic disorders, according to a study by the University of Texas Southwestern Medical Center.

DNA tests that use a process known as whole exome sequencing don’t adequately analyze more than a quarter of genes, researchers at the medical center found in a study published Jan. 6. The study also identified wide gaps in the ability of such tests to detect specific disorders from epilepsy to cancer.

“For physician and patients, they should understand that a clinical exome test may not ...