Jazz Sues Alvogen Seeking to Block Copy of Defitelio Liver Drug

April 17, 2025, 5:55 PM UTC

An Alvogen Group Inc. subsidiary’s proposed copy of Jazz Pharmaceuticals Plc’s Defitelio infringes three patents for the drug, which treats blocked veins in the liver, a federal lawsuit said.

Almaject Inc.'s generic version of the treatment for hepatic veno-occlusive disease infringes US Patent Nos. 11,085,043, 11,236,328, and 11,746,348, according to a complaint filed Wednesday in the US District Court for the District of New Jersey.

  • The patents are held by Jazz’s Gentium SRL unit, a co-plaintiff, and cover the specific formulations of Defitelio and methods for using defibrotide, its active ingredient, to treat blocked veins in the ...

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