The Patent Trial and Appeal Board determined that challenged claims of Molecular Loop Innovations LLC’s patent that relates to methods for maintaining the integrity and identification of a nucleic acid template in a multiplex sequencing reaction are unpatentable as anticipated by and obvious over prior art, in an inter partes review by Illumina Inc. According to the board, the challenged claims are anticipated by and obvious over various combinations of prior art, including prior art that describes a low-cost, high-throughput microbiome profiling method that uses combinatorial sequence tags attached to PCR primers that amplify the rRNA V6 region; titled “a ...
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