Humana Working With Mark Cuban on Potential Pharmacy Partnership

December 4, 2025, 7:35 PM UTC

Humana Inc. is working with billionaire Mark Cuban on a potential pharmacy partnership, Cuban and Humana’s chief executive officer said at a conference Thursday, a move that could step up pressure on larger pharmacy middlemen.

The remarks at the Forbes health care conference were light on details of the collaboration. Cuban, through his Cost Plus Drugs company, sells mail-order medications directly to consumers for transparent prices. Humana, which primarily sells Medicare health plans, is also expanding its pharmacy business through its CenterWell division.

Mark Cuban
Photographer: Stefani Reynolds/Bloomberg

Cuban said he was talking to Humana about “putting together direct-to-employer programs” that would bypass traditional ...

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