NIH Grant Cuts Throw Hundreds of Trials Into Chaos, Study Finds

Hundreds of federally funded clinical trials, enrolling more than 74,000 patients, were disrupted this year after the National Institutes of Health abruptly terminated billions of dollars in research grants, a study found.

Trials on prevention and infectious-disease, as well as those conducted outside the US, were the hardest hit among the more than 380 affected studies, the analysis from Harvard Medical School showed. The largest concentration of terminated projects were in the US Northeast. Cancer, cardiovascular and mental-health studies were also affected.

The cancellations mark the most extensive disruption to federally funded medical research in modern history, halting studies across ...