Monkeypox Shots Under the Skin Offer Hope for Stretching Supply

A proposal to stretch the US monkeypox vaccine supply by injecting smaller doses more superficially has promise because of the technology used to make the shot, infectious disease specialists say.

The head of the Food and Drug Administration said the agency is exploring a strategy that involves injecting a smaller dose of vaccine intradermally, or in the upper layer of the skin. The strategy, called dose sparing, could turn a one-dose vial of the vaccine into up to five separate doses.

FDA Commissioner Robert M. Califf said he expects a final decision to happen within the next few days. Bavarian ...