HHS Cancels mRNA Vaccine Projects Worth About $500 Million

Aug. 5, 2025, 9:23 PM UTC

The Department of Health and Human Services is winding down 22 mRNA vaccine development efforts under BARDA, saying the vaccines are ineffective against respiratory infections like Covid-19 and influenza.

  • Affects 22 projects worth nearly $500 million, including:
    • Canceled Moderna/UTMB contract for mRNA-based H5N1 vaccine
    • Terminated contracts with Emory University and Tiba Biotech
    • De-scoped mRNA work in contracts with Luminary Labs, ModeX, Seqirus
    • Rejected or canceled multiple pre-award mRNA solicitations, including proposals from Pfizer, Sanofi Pasteur, CSL Seqirus, Gritstone, and others
    • Restructured DoD-JPEO collaborations with AstraZeneca, HDT Bio, AAHI
  • Some final-stage mRNA projects, like with Arcturus, Amplitude, to proceed

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