Brain-Infecting Mpox Case Flags Rising Risks as Funding Shrinks

April 14, 2026, 3:29 AM UTC

A man with advanced HIV died with drug-resistant mpox replicating in his brain, US scientists found, in a case that shows how the virus can persist and evolve just as global health programs to check such infections are being scaled back.

The findings, based on a detailed autopsy by researchers at the National Institutes of Health and released as a preprint Thursday, suggest mpox can spread far beyond the skin lesions that typically define the disease. The virus was found infecting the brain and continuing to multiply there despite lower viral levels than in other tissues.

The case also showed ...

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