Health Providers Race to Navigate Pharma’s New Drug Rebate Plan

Nov. 25, 2025, 10:05 AM UTC

Thousands of health providers that treat lower-income and uninsured patients are scrambling to adjust to a new program to access steeply discounted medicines from drugmakers that stands to overhaul their operations and finances.

The 340B Rebate Model Pilot Program, administered by the US Health Resources & Services Administration, is set to significantly change how the 340B Drug Pricing Program operates after the Trump administration approved rebate models from pharmaceutical companies such as Bristol Myers Squibb Co., Johnson & Johnson, and Novo Nordisk A/S.

Drugmakers under the federal program currently provide up-front drug discounts to covered safety-net hospitals, ...

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