Tobacco companies need to step up efforts to stop kids from vaping, according to a warning from U.S. Food and Drug Administration Commissioner Scott Gottlieb.

The comments are the latest in a series of FDA efforts to crack down on companies that are producing e-cigarettes and selling them to minors. E-cigs like the products made by Juul Labs Inc. are the newest craze in underage tobacco use as youth smoking rates of combustible cigarettes hover around historic lows.

Scott Gottlieb
Photographer: Toya Sarno Jordan/Bloomberg

Tobacco companies shouldn’t build businesses that rely on getting kids hooked to nicotine, Gottlieb said in prepared remarks at the American...