Google LLC will have to defend itself against a patent infringement lawsuit in an East Texas federal court.

The U.S. Court of Appeals for the Federal Circuit Oct. 29 rejected Google’s petition to transfer the case to a different venue. District Judge J. Rodney Gilstrap had kept the lawsuit in the U.S. District Court for the Eastern District of Texas because Google had servers in the district, which qualified as “regular and established” places of business.

The Federal Circuit’s non-precedential ruling highlights the continuing questions about the U.S. Supreme Court’s 2017 decision in TC Heartland v. Kraft, which made...