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Final IRIS Assessment for Methylene Chloride
Sets Slightly Higher Lifetime Exposure Levels

Nov. 28, 2011, 5:00 AM

The final, updated toxicological review of methylene chloride released by the Environmental Protection Agency concludes that people could ingest or inhale slightly more of the solvent than the agency proposed in its draft assessment without expectation of harm.

EPA released its final toxicological review of dichloromethane (CAS No. 75-09-2), also called methylene chloride, released on Nov. 18, and posted its new conclusions on its Integrated Risk Information System (IRIS) website. The agency last revised information on methylene chloride in 1987 and 1990.

The final assessment set a reference dose (RfD) of 0.006 milligram methylene chloride per kilogram body weight per ...