Moderna Launches First Large-Scale U.S. Virus Vaccine Trial (1)

The first large study of a Covid-19 vaccine in the U.S. began with the dosing of a single patient Monday morningin Savannah, Georgia, the opening shot for testing by Moderna Inc. and the National Institutes of Health that will weigh the vaccine’s safety and efficacy in 30,000 people.

The Moderna vaccine, backed by $955 million in government funding, will be tested at 89 U.S. sites. It uses messenger RNA, a synthetic form of genetic material from the virus designed to nudge the body’s immune system into attack mode. If the trial is successful, the company is on track to ...